Research & Development

Presentations containing Hydroxytyrosol from Italian Extra Virgin Organic Olive Oil and Olive Extract.

P&P Farma is keen to confirm that, in cooperation with qualified partners in R&D, is continuously evolving to test and develop new formulations based on Hydroxytyrosol from Italian Extra Virgin Organic Olive Oil and Olive Extract.

Partners for research, development, manufacturing and product testing

• QC test for Hydroxytyrosol potency in formulation ingredients and final product carried out at Department of Chemical, Biological, Pharmaceutical and Environment Sciences (ChiBioFarAm) of the Messina University.
  The analytical method for Hydroxytyrosol QC testing in semi-solid presentation (i.e. FENÒLIA^® Eudermal Cream 15), not available at time of product development, has been specifically developed and validated [Smeriglio A., Giovinazzo C., Trombetta D. (2015) Development and Validation of RP-HPLC-DAD Method to Quantify Hydroxytyrosol Content in a Semi-Solid Pharmaceutical Formulation. Med chem 5: 442-446].


• Formulation development, manufacturing and packaging of FENÒLIA^® Enteric Coated Capsules 7.5 presentation carried out at Laboratori Truffini e Reggè Farmaceutici Srl, Milan, Italy.


• Study of Nutritional Genomics, on FENÒLIA^® Enteric Coated Capsules 7.5 carried out at the University of Rome "Tor Vergata", Section of Clinical Nutrition and Nutrigenomics.


• Enteric Coating process for FENÒLIA^® Enteric Coated Capsules 7.5 products developed and carried out at Laboratori Rofarma Italia Srl, Gaggiano, Milan, Italy,using EUDRAGUARD^® natural.


• Formulation development, manufacturing and packaging of FENÒLIA^® Cosmeceutical Line solely made for P&P Farma, at Reynaldi S.r.l., Pianezza, Turin, Italy


• Patch Test (Human Occlusive) to assess the compatibility with the human skin as absence of skin irritation on FENÒLIA^® FENÒLIA^® Eudermal Cream 15, Oleogel 90 and FENÒLIA^® Extra Virgin Olive Oil Bath 45 carried out by Chelab S.r.l., a Mérieux NutriSciences Company, Spin-Off of Padua University.


• HET-CAM Test for detecting ocular irration of FENÒLIA^® Extra Virgin Olive Oil Shampoo 40 on Chorioallantoic Membrane carried out by ISPE S.r.l., Institut for Skin and Product Evaluation, Milan Italy.

EUDRAGUARD^® is a registered trademark of Evonik Industries AG